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2016WHO髓系肿瘤分类（中英对照）
2018-09-14 21:30 阅读(2731) 评论(0) 分类：翻译分享
在2008年第4版WHO分类发表8年后，WHO分类进行了一次更新（但不是第5版），即《淋巴造血肿瘤WHO分类》2016年第4版更新。
| 2016 World Health Organization Classification of Myeloid Neoplasms | 髓系肿瘤WHO分类（2016） | ||||
| Myeloproliferative Neoplasms | 骨髓增殖性肿瘤（MPN） | ||||
| Chronic myeloid leukemia, BCR-ABL1 positive | BCR-ABL1阳性慢性髓系白血病（BCR-ABL1+CML） | ||||
| Chronic neutrophilic leukemia | 慢性中性粒细胞白血病（CNL） | ||||
| Polycythemia vera | 真性红细胞增生症（PV） | ||||
| Primary myelofibrosis | 原发性骨髓纤维化(PMF) | ||||
| Essential thrombocythemia | 原发性血小板增生症（ET） | ||||
| Chronic eosinophilic, not otherwise specified | 慢性嗜酸粒细胞白血病-非特指（CEL-NOS） | ||||
| Myeloproliferative neoplasm, unclassifiable | 骨髓增殖性肿瘤-无法分类（MPN-U） | ||||
| Mastocytosis | 肥大细胞增生症（MCD） | ||||
| Cutaneous mastocytosis | 皮肤肥大细胞增生症 | ||||
| Systemic mastocytosis | 系统性肥大细胞增生症 | ||||
| Mast cell sarcoma | 肥大细胞肉瘤 | ||||
| Myeloid/Lymphoid Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, or FGFR1 or with PCM1-JAK2 | 髓系/淋巴系肿瘤伴嗜酸粒细胞增多和PDGFRA、PDGFRB或FGFR1异常 | ||||
| Myeloid/lymphoid neoplasms with PDGFRA rearrangement | 髓系/淋巴系肿瘤伴PDGFRA重排 | ||||
| Myeloid/lymphoid neoplasms with PDGFRB rearrangement | 髓系/淋巴系肿瘤伴PDGFRB重排 | ||||
| Myeloid/lymphoid neoplasms with FGFR1 rearrangement | 髓系/淋巴系肿瘤伴FGFR1重排 | ||||
| Myeloid/lymphoid neoplasms with PCM1-JAK2 | 髓系/淋巴系肿瘤伴PCM1-JAK2 | ||||
| Myelodysplastic/Myeloproliferative Neoplasms | 骨髓增生异常/骨髓增殖性肿瘤（MDS/MPN） | ||||
| Chronic myelomonocytic leukemia | 慢性粒-单核细胞白血病（CMML） | ||||
| Chronic myelomonocytic leukemia 0 | 慢性粒-单核细胞白血病0 | ||||
| Chronic myelomonocytic leukemia 1 | 慢性粒-单核细胞白血病1 | ||||
| Chronic myelomonocytic leukemia 2 | 慢性粒-单核细胞白血病2 | ||||
| Atypical chronic myeloid leukemia, BCR-ABL1 negative | BCR-ABL1阴性不典型慢性髓系白血病（BCR-ABL1-aCML） | ||||
| Juvenile myelomonocytic leukemia | 幼年性粒-单核细胞白血病（JMML） | ||||
| Myelodysplastic/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis | 骨髓增生异常/骨髓增殖性肿瘤伴环形铁粒幼细胞和血小板增多（MDS/MPN-RS-T） | ||||
| Myelodysplastic/myeloproliferative neoplasm, unclassifiable | 骨髓增生异常/骨髓增殖性肿瘤-无法分类（MDS/MPN-U） | ||||
| Myelodysplastic Syndromes/Neoplasms | 骨髓增生异常综合征/肿瘤（MDS） | ||||
| Myelodysplastic syndrome with single lineage dysplasia | 骨髓增生异常综合征伴单系病态造血 | ||||
| Myelodysplastic syndrome with ring sideroblasts | 骨髓增生异常综合征伴环形铁粒幼细胞 | ||||
| Myelodysplastic syndrome with ring sideroblasts and single lineage dysplasia | 骨髓增生异常综合征伴环形铁粒幼细胞和单系病态造血 | ||||
| Myelodysplastic syndrome with ring sideroblasts and multilineage dysplasia | 骨髓增生异常综合征伴环形铁粒幼细胞和多系病态造血 | ||||
| Myelodysplastic syndrome with multilineage dysplasia | 骨髓增生异常综合征伴多系病态造血 | ||||
| Myelodysplastic syndrome with excess blasts | 骨髓增生异常综合征伴原始细胞过多 | ||||
| Myelodysplastic syndrome with excess blasts 1 | 骨髓增生异常综合征伴原始细胞过多1 | ||||
| Myelodysplastic syndrome with excess blasts 2 | 骨髓增生异常综合征伴原始细胞过多2 | ||||
| Myelodysplastic syndrome with isolated del(5q) | 骨髓增生异常综合征伴孤立性5q缺失 | ||||
| Myelodysplastic syndrome, unclassifiable | 骨髓增生异常综合征-无法分类（MDS-U） | ||||
| Childhood myelodysplastic syndrome | 儿童骨髓增生异常综合征 | ||||
| Refractory cytopenia of childhood | 儿童难治性血细胞减少（RCC） | ||||
| Myeloid Neoplasms with Germline Predisposition | 髓系肿瘤伴种系易感性 | ||||
| Acute Myeloid Leukemia and Related Precursor Neoplasms | 急性髓系白血病（AML）和相关前驱肿瘤 | ||||
| Acute myeloid leukemia with recurrent genetic abnormalities | AML伴重现性遗传学异常 | ||||
| Acute myeloid leukemia with t(8;21)(q22;q22.1); RUNX1-RUNX1T1 | AML伴t(8;21)(q22;q22.1);RUNX1-RUNX1T1 | ||||
| Acute myeloid leukemia with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11 | AML伴inv(16)(p13.1q22)或t(16;16)(p13.1;q22);CBFB-MYH11 | ||||
| Acute promyelocytic leukemia with PML-RARA | 急性早幼粒细胞白血病(APL)伴t(15;17)(q22，q12);PML-RARA | ||||
| Acute myeloid leukemia with t(9;11)(p21.3;q23.3); KMT2A-MLLT3 | AML伴t(9;11)(p21.3，q23.3);KMT2A-MALT3 | ||||
| Acute myeloid leukemia with t(6;9)(p23;q34.1); DEK-NUP214 | AML伴t(6：9)(p23，q34.1);DEK-NUP214 | ||||
| Acute myeloid leukemia with inv(3)(q21.3q26.2) or (3;3)(q21.3;q26.2); GATA2, MECOM (EVI1) | AML伴inv(3)(q21.3q26.2)或t(3;3)(q21.3;q26.2);GATA2, MECOM (EVI1) | ||||
| Acute myeloid leukemia (megakaryoblastic) with t(1;22)(p13.3;q13.1); RBM15-MKL1 | AML(原巨核细胞)伴t(1;22)(p13.3;q13.1);RBM15-MKL1 | ||||
| Acute myeloid leukemia with BCR-ABL1 | AML伴BCR-ABL1 | ||||
| Acute myeloid leukemia with gene mutations | AML伴基因突变 | ||||
| Acute myeloid leukemia with mutated NPM1 | AML伴突变性NPM1 | ||||
| Acute myeloid leukemia with biallelic mutations of CEBPA | AML伴CEBPA双等位基因突变 | ||||
| Acute myeloid leukemia with mutated RUNX1 | AML伴突变性RUNX1 | ||||
| Acute myeloid leukemia with myelodysplasia-related changes | AML伴骨髓增生异常相关改变（AML-MRC) | ||||
| Therapy-related myeloid neoplasms | 治疗相关的髓系肿瘤 | ||||
| Acute myeloid leukemia, not otherwise specified | 急性髓系白血病-非特指（AML-NOS） | ||||
| Acute myeloid leukemia with minimal differentiation | AML伴微分化 | ||||
| Acute myeloid leukemia without maturation | AML不伴成熟 | ||||
| Acute myeloid leukemia with maturation | AML伴成熟 | ||||
| Acute myelomonocytic leukemia | 急性粒-单核细胞白血病（AMML） | ||||
| Acute monoblastic and monocytic leukemia | 急性原单核细胞和单核细胞白血病 | ||||
| Acute erythroid leukemia | 急性红系白血病 | ||||
| Acute megakaryoblastic leukemia | 急性原巨核细胞白血病 | ||||
| Acute basophilic leukemia | 急性嗜碱粒细胞白血病 | ||||
| Acute panmyelosis with myelofibrosis | 急性全髓增殖症伴骨髓纤维化（APMF） | ||||
| Myeloid sarcoma | 髓系肉瘤 | ||||
| Myeloid proliferations related to Down syndrome | 唐氏综合征相关髓系增殖性疾病/症 | ||||
| Transient abnormal myelopoiesis associated with Down syndrome | 一过性髓系异常造血伴唐氏综合征 | ||||
| Myeloid leukemia associated with Down syndrome | 唐氏综合征相关髓系白血病 | ||||
| Acute Leukemias of Ambiguous Lineage | 不明细胞系急性白血病 | ||||
| Acute undifferentiated leukemia | 急性未分化白血病 | ||||
| Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1 | 混合表型急性白血病伴t(9;22)(q34.1;q11.2);BCR-ABL1 | ||||
| Mixed phenotype acute leukemia with t(v;11q23.3); KMT2A rearranged | 混合表型急性白血病伴t(v;11q23.3);KMT2A重排 | ||||
| Mixed phenotype acute leukemia, B/myeloid, not otherwise specified | 混合表型急性白血病，B／髓系，非特指 | ||||
| Mixed phenotype acute leukemia, T/myeloid, not otherwise specified | 混合表型急性白血病，T／髓系，非特指 | ||||
| Mixed phenotype acute leukemia, not otherwise specified-rare types | 混合表型急性白血病，非特指，罕见型 | ||||
| Acute leukemias of ambiguous lineage, not otherwise specified | 不明细胞系急性白血病，非特指 | ||||
| 附：髓系细胞发育 | |||
| colony-forming unit-megakaryocyte | 巨核细胞集落形成单位（CFU-MK） | ||
| common myeloid progenitor | 共同髓系祖细胞（CMP） | ||
| granulocyte-monocyte progenitor | 粒单系祖细胞（GMP） | ||
| hematopoietic stem cell | 造血干细胞（HSC） | ||
| Proerythroblast | 原红细胞 | ||
| Basophilic erythroblast | 早幼红细胞 | ||
| Polychromatic erythroblast | 中幼红细胞 | ||
| Orthochromatic erythroblast | 晚幼红细胞 | ||
| Monoblast | 原单核细胞 | ||
| Promonocyte | 幼单核细胞 | ||
| Monocyte | 单核细胞 | ||
| Macrophage | 巨噬细胞 | ||
| Myeloblast | 原粒细胞 | ||
| Promyelocyte | 早幼粒细胞 | ||
| Myelocyte | 中幼粒细胞 | ||
| Metamyelocyte | 晚幼粒细胞 | ||
| Neutrophil | 中性粒细胞 | ||
| Megakaryoblast | 原巨核细胞 | ||
| Immature megakaryocyte | 幼巨核细胞 | ||
| Mature megakaryocyte | 成熟巨核细胞 | ||
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