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癌、间皮瘤和反应性间皮细胞的免疫组化鉴别

2015-05-16 12:48  阅读(2036)  评论(0)  分类:专业

癌、间皮瘤和反应性间皮细胞的免疫组化鉴别


 

上皮型间皮瘤和腺癌中免疫组化标记物表达

标记物

上皮型间皮瘤

腺癌

间皮瘤相关标记物


CK5/6

562/651(86.3%)

81/614(13.2%)

Calretinin

905/1071(84.5%)

146/980(14.9%)

WT-1

254/329(77.2%)

9/213(4.2%)

MC

709/834(85%)

74/202(36.6%)

h-Caldesmon

68/70(97%)

0/70(0%)

D2-40

113/119(95%)

2/80(3%)

Vimentin

528/838(63%)

133/883(15.1%)

腺癌相关标记物


Ber-EP4

98/969(9.2%)

695/840(82.7%)

CEA

91/1888(4.8%)

1408/1662(84.7%)

MOC-31

19/276(6.9%)

257/281(91.5%)

CA72.4

56/770(7.3%)

668/839(79.6%)

CD15

88/1274(6.9%)

1185/1611(73.6%)

TTF-1

0/240(0%)

264/366(72%)



恶性间皮瘤与肺腺癌与卵巢浆液性腺癌的免疫组化鉴别诊断

 

标记物

恶性间皮瘤

肺腺癌

卵巢浆液性腺癌

calretinin

+

-

-

CK5/6

+

-/+

-/+

WT-1

+

-

+

D2-40

+

-

-

CEA(单克隆)

-

+

-/+

MOC-31

-

+

+

B72.3

-

+

+

BG8

-

+

+/-

Ber-EP4

-

+

+

TTF-1

-

+

-

NapsinA

-

+

-

PAX8

-

-

+

ERPR

-

-

+


 

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