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鼻咽非角化鳞状细胞癌WHO部分翻译
The undifferentiated subtype, which is more common, is characterized by large tumour cells with a syncytial appearance, round to oval vesicular nuclei, and large central nucleoli. The nuclei can be chromatin-rich rather than vesicular and the neoplastic cells generally have scant amphophilic or eosinophilic cytoplasm. The malignant cells can assume spindle-cell features in fascicular arrangements.
未分化亚型更为常见,是具有合胞体外观的拥有属性大型肿瘤细胞,圆形至卵圆形泡状核,以及大型中央核仁。细胞核可以是富含染色质的而不是泡状的,肿瘤细胞通常很少有双嗜性或嗜酸性胞浆。恶性肿瘤细胞呈梭形细胞特征,呈束状排列。
The differentiated subtype exhibits cellular stratification and pavementing, often with plexiform growth; occasional keratinized cells may be present. Compared with those in the undifferentiated subtype, the neoplastic cells are often slightly smaller, the N: C ratio is lower, the nuclei are often more chromatin-rich and the nucleoli are usually less prominent, Focally, intercellular bridges may be present.
已分化的亚型表现出细胞分层和膜状生长,通常呈丛状生长,偶尔可见角化细胞。与未分化亚型相比,肿瘤细胞通常较小,n: c 比值较低,细胞核染色质丰富,核仁不明显,局灶性、细胞间桥梁可能存在。
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