我的博文

2016WHO髓系肿瘤分类(中英对照)

2018-09-14 21:30  阅读(137)  评论(0)  分类:翻译分享

在2008年第4版WHO分类发表8年后,WHO分类进行了一次更新(但不是第5版),即《淋巴造血肿瘤WHO分类》2016年第4版更新。

2016 World Health Organization Classification of Myeloid   Neoplasms髓系肿瘤WHO分类(2016)
Myeloproliferative   Neoplasms
骨髓增殖性肿瘤(MPN)
Chronic   myeloid leukemia, BCR-ABL1 positiveBCR-ABL1阳性慢性髓系白血病(BCR-ABL1+CML)
Chronic   neutrophilic leukemia
慢性中性粒细胞白血病(CNL)
Polycythemia   vera

真性红细胞增生症(PV)
Primary   myelofibrosis
原发性骨髓纤维化(PMF)
Essential   thrombocythemia
原发性血小板增生症(ET)
Chronic   eosinophilic, not otherwise specified慢性嗜酸粒细胞白血病-非特指(CEL-NOS)
Myeloproliferative   neoplasm, unclassifiable骨髓增殖性肿瘤-无法分类(MPN-U)
Mastocytosis

肥大细胞增生症(MCD)
Cutaneous   mastocytosis
皮肤肥大细胞增生症
Systemic   mastocytosis
系统性肥大细胞增生症
Mast cell   sarcoma

肥大细胞肉瘤
Myeloid/Lymphoid   Neoplasms with Eosinophilia and Rearrangement of PDGFRA, PDGFRB, or FGFR1 or   with PCM1-JAK2髓系/淋巴系肿瘤伴嗜酸粒细胞增多和PDGFRA、PDGFRB或FGFR1异常
Myeloid/lymphoid   neoplasms with PDGFRA rearrangement髓系/淋巴系肿瘤伴PDGFRA重排
Myeloid/lymphoid   neoplasms with PDGFRB rearrangement髓系/淋巴系肿瘤伴PDGFRB重排
Myeloid/lymphoid   neoplasms with FGFR1 rearrangement髓系/淋巴系肿瘤伴FGFR1重排
Myeloid/lymphoid   neoplasms with PCM1-JAK2髓系/淋巴系肿瘤伴PCM1-JAK2
Myelodysplastic/Myeloproliferative   Neoplasms骨髓增生异常/骨髓增殖性肿瘤(MDS/MPN)
Chronic   myelomonocytic leukemia
慢性粒-单核细胞白血病(CMML)

Chronic myelomonocytic leukemia 0
慢性粒-单核细胞白血病0

Chronic myelomonocytic leukemia 1
慢性粒-单核细胞白血病1

Chronic myelomonocytic leukemia 2
慢性粒-单核细胞白血病2
Atypical   chronic myeloid leukemia, BCR-ABL1 negativeBCR-ABL1阴性不典型慢性髓系白血病(BCR-ABL1-aCML)
Juvenile   myelomonocytic leukemia
幼年性粒-单核细胞白血病(JMML)
Myelodysplastic/myeloproliferative   neoplasm with ring sideroblasts and thrombocytosis骨髓增生异常/骨髓增殖性肿瘤伴环形铁粒幼细胞和血小板增多(MDS/MPN-RS-T)
Myelodysplastic/myeloproliferative   neoplasm, unclassifiable骨髓增生异常/骨髓增殖性肿瘤-无法分类(MDS/MPN-U)
Myelodysplastic   Syndromes/Neoplasms骨髓增生异常综合征/肿瘤(MDS)
Myelodysplastic   syndrome with single lineage dysplasia骨髓增生异常综合征伴单系病态造血
Myelodysplastic   syndrome with ring sideroblasts骨髓增生异常综合征伴环形铁粒幼细胞

Myelodysplastic syndrome with ring   sideroblasts and single lineage dysplasia
骨髓增生异常综合征伴环形铁粒幼细胞和单系病态造血

Myelodysplastic syndrome with ring   sideroblasts and multilineage dysplasia
骨髓增生异常综合征伴环形铁粒幼细胞和多系病态造血
Myelodysplastic   syndrome with multilineage dysplasia骨髓增生异常综合征伴多系病态造血
Myelodysplastic   syndrome with excess blasts骨髓增生异常综合征伴原始细胞过多

Myelodysplastic syndrome with excess   blasts 1
骨髓增生异常综合征伴原始细胞过多1

Myelodysplastic syndrome with excess   blasts 2
骨髓增生异常综合征伴原始细胞过多2
Myelodysplastic   syndrome with isolated del(5q)骨髓增生异常综合征伴孤立性5q缺失
Myelodysplastic   syndrome, unclassifiable骨髓增生异常综合征-无法分类(MDS-U)
Childhood   myelodysplastic syndrome
儿童骨髓增生异常综合征

Refractory cytopenia of   childhood
儿童难治性血细胞减少(RCC)
Myeloid   Neoplasms with Germline Predisposition髓系肿瘤伴种系易感性
Acute   Myeloid Leukemia and Related Precursor Neoplasms急性髓系白血病(AML)和相关前驱肿瘤
Acute   myeloid leukemia with recurrent genetic abnormalitiesAML伴重现性遗传学异常

Acute myeloid leukemia with   t(8;21)(q22;q22.1); RUNX1-RUNX1T1
AML伴t(8;21)(q22;q22.1);RUNX1-RUNX1T1

Acute myeloid leukemia   with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11
AML伴inv(16)(p13.1q22)或t(16;16)(p13.1;q22);CBFB-MYH11

Acute promyelocytic leukemia with   PML-RARA
急性早幼粒细胞白血病(APL)伴t(15;17)(q22,q12);PML-RARA

Acute myeloid leukemia with   t(9;11)(p21.3;q23.3); KMT2A-MLLT3
AML伴t(9;11)(p21.3,q23.3);KMT2A-MALT3

Acute myeloid leukemia with   t(6;9)(p23;q34.1); DEK-NUP214
AML伴t(6:9)(p23,q34.1);DEK-NUP214

Acute myeloid leukemia   with inv(3)(q21.3q26.2) or (3;3)(q21.3;q26.2); GATA2, MECOM (EVI1)
AML伴inv(3)(q21.3q26.2)或t(3;3)(q21.3;q26.2);GATA2, MECOM (EVI1)

Acute myeloid leukemia   (megakaryoblastic) with t(1;22)(p13.3;q13.1); RBM15-MKL1
AML(原巨核细胞)伴t(1;22)(p13.3;q13.1);RBM15-MKL1

Acute myeloid leukemia   with BCR-ABL1
AML伴BCR-ABL1
Acute   myeloid leukemia with gene mutationsAML伴基因突变

Acute myeloid leukemia with mutated   NPM1
AML伴突变性NPM1

Acute myeloid leukemia with   biallelic mutations of CEBPA
AML伴CEBPA双等位基因突变

Acute myeloid leukemia with mutated   RUNX1
AML伴突变性RUNX1
Acute   myeloid leukemia with myelodysplasia-related changesAML伴骨髓增生异常相关改变(AML-MRC)
Therapy-related   myeloid neoplasms
治疗相关的髓系肿瘤
Acute   myeloid leukemia, not otherwise specified急性髓系白血病-非特指(AML-NOS)

Acute myeloid leukemia with minimal   differentiation
AML伴微分化

Acute myeloid leukemia without   maturation
AML不伴成熟

Acute myeloid leukemia with   maturation
AML伴成熟

Acute myelomonocytic leukemia
急性粒-单核细胞白血病(AMML)

Acute monoblastic and monocytic   leukemia
急性原单核细胞和单核细胞白血病

Acute erythroid leukemia

急性红系白血病

Acute megakaryoblastic leukemia
急性原巨核细胞白血病

Acute basophilic leukemia

急性嗜碱粒细胞白血病

Acute panmyelosis with myelofibrosis
急性全髓增殖症伴骨髓纤维化(APMF)
Myeloid   sarcoma

髓系肉瘤
Myeloid   proliferations related to Down syndrome唐氏综合征相关髓系增殖性疾病/症

Transient abnormal myelopoiesis   associated with Down syndrome
一过性髓系异常造血伴唐氏综合征

Myeloid leukemia associated with   Down syndrome
唐氏综合征相关髓系白血病
Acute   Leukemias of Ambiguous Lineage不明细胞系急性白血病
Acute   undifferentiated leukemia
急性未分化白血病
Mixed   phenotype acute leukemia with t(9;22)(q34.1;q11.2); BCR-ABL1混合表型急性白血病伴t(9;22)(q34.1;q11.2);BCR-ABL1
Mixed   phenotype acute leukemia with t(v;11q23.3); KMT2A rearranged混合表型急性白血病伴t(v;11q23.3);KMT2A重排
Mixed   phenotype acute leukemia, B/myeloid, not otherwise specified混合表型急性白血病,B/髓系,非特指
Mixed   phenotype acute leukemia, T/myeloid, not otherwise specified混合表型急性白血病,T/髓系,非特指
Mixed   phenotype acute leukemia, not otherwise specified-rare types混合表型急性白血病,非特指,罕见型
Acute   leukemias of ambiguous lineage, not otherwise specified不明细胞系急性白血病,非特指
附:髓系细胞发育

colony-forming   unit-megakaryocyte巨核细胞集落形成单位(CFU-MK)
common   myeloid progenitor共同髓系祖细胞(CMP)
granulocyte-monocyte   progenitor粒单系祖细胞(GMP)
hematopoietic   stem cell造血干细胞(HSC)
Proerythroblast
原红细胞
Basophilic   erythroblast 早幼红细胞
Polychromatic   erythroblast 中幼红细胞
Orthochromatic   erythroblast 晚幼红细胞
Monoblast 
原单核细胞
Promonocyte 
幼单核细胞
Monocyte 
单核细胞
Macrophage 
巨噬细胞
Myeloblast 
原粒细胞 
Promyelocyte 
早幼粒细胞
Myelocyte 
中幼粒细胞
Metamyelocyte 
晚幼粒细胞
Neutrophil 
中性粒细胞
Megakaryoblast 
原巨核细胞
Immature   megakaryocyte 幼巨核细胞
Mature   megakaryocyte 成熟巨核细胞


我要评论

0条评论